.png){kind=icon}
.png){kind=icon}
Return
FDA-approved fulvestrant-induced CAR phase separation enables precise control of CAR T antitumor function
.png){kind=icon}
PRE
AI
Q
K
X
H
J
L
Z
J
G
H
DOI：10.1016/j.stem.2026.06.005.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• Design of a fulvestrant-induced phase-separation (DiPS) module via an engineered ERα variant • The DiPS module enables drug-inducible CAR clustering in T cells (iPhase-CAR) • The iPhase-CAR system enables fast-acting and reversible promotion of CAR T cell functions • iPhase-CAR T cells demonstrate superior cytotoxic potency
Journal
IF:
20.4
Papers:
3.6K
Citations:
3.1W
Organization
Cited Papers