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Federated Fine-Tuning of SAM-Med3D for MRI-Based Dementia Classification

delete2026-01-01
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PRE
AI
K
Kaouther Mouheb *
M
Marawan Elbatel
J
Janne M. Papma
G
Geert Jan Biessels
J
Jurgen A.H.R. Claassen
H
Huub A. M. Middelkoop
B
Barbara C. Van Munster
W
Wiesje M. van der Flier
I
Inez Ramakers
S
Stefan Klein
E
Esther E. Bron
DOI:10.1007/978-3-032-05663-4_7delete
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Abstract

Abstract

En 中文
While foundation models (FMs) offer strong potential for AI-based dementia diagnosis, their integration into federated learning (FL) systems remains underexplored. In this benchmarking study, we systematically evaluate the impact of key design choices: classification head architecture, fine-tuning strategy, and aggregation method, on the performance and efficiency of federated FM tuning using brain MRI data. Using a large multi-cohort dataset, we find that the architecture of the classification head substantially influences performance, freezing the FM encoder achieves comparable results to full fine-tuning, and advanced aggregation methods outperform standard federated averaging. Our results offer practical insights for deploying FMs in decentralized clinical settings and highlight trade-offs that should guide future method development.
Keywords:
Federated learning
Foundation models
Dementia
MRI

Journal

B
BRIDGING REGULATORY SCIENCE AND MEDICAL IMAGING EVALUATION; AND DISTRIBUTED, COLLABORATIVE, AND FEDERATED LEARNING, MICCAI 2025
IF:
0
Papers:
15
Citations:
0

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Utrecht University
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L
leiden university
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E
erasmus university rotterdam
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2.4K
Papers: 1.0K
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U
utrecht university medical center
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439
Papers: 248
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H
hong kong university of science & technology
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494
Papers: 271
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R
Radboud University Nijmegen
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Papers: 3.4W
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E
erasmus mc
Scholars:
2.0K
Papers: 1.1K
Citations: 212
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