.png){kind=icon}
返回
Fibromyalgia
.png){kind=icon}
PRE
AI
DOI：10.1038/nrdp.2015.22.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Fibromyalgia is a common illness characterized by chronic widespread pain, sleep problems (including unrefreshing sleep), physical exhaustion and cognitive difficulties. The definition, pathogenesis and treatment are controversial, and some even contest the existence of this disorder. In 1990, the American College of Rheumatology (ACR) defined classification criteria that required multiple tender points (areas of tenderness occurring in muscles and muscle-tendon junctions) and chronic widespread pain. In 2010, the ACR preliminary diagnostic criteria excluded tender points, allowed less extensive pain and placed reliance on patient-reported somatic symptoms and cognitive difficulties. Fibromyalgia occurs in all populations worldwide, and symptom prevalence ranges between 2% and 4% in the general population. The prevalence of people who are actually diagnosed with fibromyalgia ('administrative prevalence') is much lower. A model of fibromyalgia pathogenesis has been suggested in which biological and psychosocial variables interact to influence the predisposition, triggering and aggravation of a chronic disease, but the details are unclear. Diagnosis requires the history of a typical cluster of symptoms and the exclusion of a somatic disease that sufficiently explains the symptoms by medical examination. Current evidence-based guidelines emphasize the value of multimodal treatments, which encompass both non-pharmacological and selected pharmacological treatments tailored to individual symptoms, including pain, fatigue, sleep problems and mood problems. For an illustrated summary of this Primer, visit: http://go.nature.com/LIBdDX
Keyword:
QUALITY-OF-LIFE
PRELIMINARY DIAGNOSTIC-CRITERIA
INTRINSIC BRAIN CONNECTIVITY
CHRONIC-FATIGUE-SYNDROME
CEREBROSPINAL-FLUID
DOUBLE-BLIND
RHEUMATIC-DISEASES
GENERAL-POPULATION
CONTROLLED-TRIAL
CENTRAL SENSITIZATION
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
N
IF:
60.6
论文数:
648
被引数:
3.8W
机构
引用论文
分享收藏A two-dimensional thin Co-MOF nanosheet as a nanozyme with high oxidase-like activity for GSH detection二维薄co-mof纳米片作为具有高氧化酶样活性的纳米酶，用于GSH检测
PREAI
分享收藏Mortality in Fibromyalgia: A Study of 8,186 Patients Over Thirty-Five Years纤维肌痛的死亡率: 35年8,186例患者的研究
OAAI
OAAI分享收藏The Prevalence of Fibromyalgia in the General Population A Comparison of the American College of Rheumatology 1990, 2010, and Modified 2010 Classification Criteria.png)
ARTHRITIS & RHEUMATOLOGYOAAI
ARTHRITIS & RHEUMATOLOGYIF10.9
OAAI分享收藏Characteristics of Fibromyalgia Independently Predict Poorer Long-Term Analgesic Outcomes Following Total Knee and Hip ArthroplastyARTHRITIS & RHEUMATOLOGYOAAI
ARTHRITIS & RHEUMATOLOGYIF10.9
OAAI分享收藏Quetiapine extended-release (Seroquel-XR) versus amitriptyline monotherapy for treating patients with fibromyalgia: a 16-week, randomized, flexible-dose, open-label trialPSYCHOPHARMACOLOGY
PSYCHOPHARMACOLOGYIF3.3
PREAI
分享收藏
查看更多内容