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Food-derived bioactive compounds in ocular diseases: Molecular mechanisms, clinical evidence, and translational challenges
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DOI：10.1016/j.jnutbio.2026.110465.png)
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Abstract
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• Lutein and zeaxanthin increase macular pigment and improve visual function in AMD. • Omega-3s reduce ocular inflammation and benefits dry eye and retinal health. • Polyphenols show strong experimental retinal neuroprotection but limited clinical validation. • Nutraceutical efficacy is constrained by bioavailability, dosage, and tissue-target delivery.
Keywords:
Nutraceuticals
Antioxidants
Oxidative stress
Polyphenols
Omega-3 fatty acids
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