Frailty

John E. Morley

doi:10.1016/j.mcna.2006.05.019

2006-09-01

129

PRE

DOI：10.1016/j.mcna.2006.05.019

原文链接

摘要

En 中文

Frailty is a condition that now can be objectively defined by the Fried criteria. Frail people are at risk for rapid deterioration when exposed to stressful events. The causes of frailty are multifactorial and include sarcopenia, protein energy malnutrition, pain, and various disease processes, such as anemia, diabetes mellitus, depression, and congestive heart failure. At the pathophysiologic level, elevated proinflammatory cytokine, low vitamin D, and low testosterone levels (in men and possibly women) all play a role in the genesis of frailty.

Keyword:

SKELETAL-MUSCLE MASS

RANDOMIZED CONTROLLED-TRIAL

AGED AFRICAN-AMERICANS

OLDER PERSONS

PHYSICAL PERFORMANCE

DIABETES-MELLITUS

TESTOSTERONE REPLACEMENT

LONGITUDINAL CHANGES

HEMOGLOBIN LEVELS

AGING PROCESS

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期刊

Medical Clinics of North America

IF:

4.2

论文数:

2.6K

被引数:

7.5K

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暂无机构信息

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