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Free-paced high-performance brain-computer interfaces
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DOI：10.1088/1741-2560/4/3/018.png)
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Abstract
En 中文
Neural prostheses aim to improve the quality of life of severely disabled patients by translating neural activity into control signals for guiding prosthetic devices or computer cursors. We recently demonstrated that plan activity from premotor cortex, which specifies the endpoint of the upcoming arm movement, can be used to swiftly and accurately guide computer cursors to the desired target locations. However, these systems currently require additional, non-neural information to specify when plan activity is present. We report here the design and performance of state estimator algorithms for automatically detecting the presence of plan activity using neural activity alone. Prosthesis performance was nearly as good when state estimation was used as when perfect plan timing information was provided separately (similar to 5 percentage points lower, when using 200 ms of plan activity). These results strongly suggest that a completely neurally-driven high-performance brain-computer interface is possible.
Keywords:
NEUROPROSTHETIC DEVICES
PREPARATORY ACTIVITY
NEURONAL ENSEMBLES
NEURAL PROSTHETICS
MOVEMENT ACTIVITY
CORTICAL CONTROL
PREMOTOR CORTEX
CONTROL SIGNALS
MOTOR
VARIABILITY
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