Fresh frozen plasma-first approach is independently associated with improved survival in severely injured patients undergoing massive transfusion

Allyson M. Hynes

doi:10.1097/TA.0000000000005093

Fresh frozen plasma-first approach is independently associated with improved survival in severely injured patients undergoing massive transfusion

2026-06-11

0

PRE

AI

A

Allyson M. Hynes

W

Westein, Riley J. MD

T

Turner, Tyler J. MD

C

Conrardy, Ryan D. MS

Y

Yang, Kai PhD

B

Boyle, Kelly A. MD

L

Levin, Jeremy H. MD

D

de Moya, Marc A. MD, FACS

DOI：10.1097/TA.0000000000005093

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Despite evidence supporting high fresh frozen plasma (FFP)–to–packed red blood cell (PRBC) ratios, the optimal initial blood product in severe injury is unknown. We hypothesized that an FFP-first approach is associated with improved survival.

Keywords:

Coagulopathy

hemorrhagic

massive transfusion

shock

resuscitation

Fresh frozen plasma-first approach is independently associated with improved survival in severely injured patients undergoing massive transfusion

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