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Functional phytochemicals from Ocimum gratissimum mitigate lipopolysaccharide-induced oxidative stress and inflammation via modulation of antioxidant and inflammatory pathways
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DOI：10.1016/j.jff.2026.107386.png)
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Abstract
En 中文
• OGME improved survival in LPS-induced endotoxemia. • OGME restored antioxidant defence and reduced lipid peroxidation. • OGME suppressed TNF-α, IL-6, NF-κB, and MAPK14 expression. • Naringenin showed strong binding to KEAP1 and MAPK14.
Keywords:
Ocimum gratissimum
Dietary phytochemicals
Inflammation
Oxidative stress
Nutraceuticals
Functional food
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