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FUS maintains TAZ fluidity and function
DOI:10.1038/s41556-023-01318-2.png)
Abstract
En 中文
The transcriptional coactivators TAZ and YAP pair with transcriptional enhanced associate domains (TEADs) to regulate transcription. TAZ and YAP nuclear condensates ensure optimal transcription. A new study reports that FUS regulates TAZ condensates by maintaining them in a fluid state to drive transcription of target genes.
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