GALA, a database for genomic sequence alignments and annotations

Belinda Giardine

doi:10.1101/gr.603103

2003-04-01

DOI：10.1101/gr.603103

原文链接

查看原文

摘要

En 中文

We have developed a relational database to contain whole genome sequence alignments between human and mouse with extensive annotations of the human sequence. Complex queries are supported on recorded features, both directly and on proximity among them. Searches can reveal a wide variety of relationships, such as finding all genes expressed in a designated tissue that have a highly conserved noncoding sequence S' to the start site. Other examples are finding single nucleotide polymorphisms that occur in conserved noncoding regions upstream of genes and identifying CpG islands that overlap the S' ends of divergently transcribed genes. The database is available online at http:/ /globin.cse.psu.edu / and http:/ / bio.cse.psu.edu /.

Keyword:

MOUSE

RECOMBINATION

STRATEGIES

REGION

CIS

MAP

AI总结

对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。

期刊

Genome Research

IF:

5.5

论文数:

5.6K

被引数:

4.3W

机构

暂无机构信息

引用论文

Journal of Polymer Science Part A: Polymer Chemistry

IF0

2017-06-15

PREAI

Helicobacter pylori recrudescence and its influencing factors

Journal of Cellular and Molecular Medicine

IF0

2019-09-19

OAAI

Yan Sun; Jun Zhang

Comprehensive human genetic maps: Individual and sex-specific variation in recombination

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

1998-09-01

1.0K

OAAI

Broman, KW; Murray, JC; Sheffield, VC; White, RL; Weber, JL

Evolutionary strategies for the elucidation of cis and trans factors that regulate the developmental switching programs of the beta-like globin genes

MOLECULAR PHYLOGENETICS AND EVOLUTION

IF3.6

1996-02-01

PREAI

Gumucio, DL; Shelton, DA; Zhu, W; Millinoff, D; Gray, T; Bock, JH; Slightom, JL; Goodman, M

Long human-mouse sequence alignments reveal novel regulatory elements: A reason to sequence the mouse genome

GENOME RESEARCH

IF5.5

1997-10-01

299

OAAI

Hardison, RC; Oeltjen, J; Miller, W

The Ensembl genome database project

NUCLEIC ACIDS RESEARCH

IF13.1

2002-01-01

1.3K

OAAI

Hubbard, T; Barker, D; Birney, E; Cameron, G; Chen, Y; Clark, L; Cox, T; Cuff, J; Curwen, V; Down, T; Durbin, R; Eyras, E; Gilbert, J; Hammond, M; Huminiecki, L; Kasprzyk, A; Lehvaslaiho, H; Lijnzaad, P; Melsopp, C; Mongin, E; Pettett, R; Pocock, M; Potter, S; Rust, A; Schmidt, E; Searle, S; Slater, G; Smith, J; Spooner, W; Stabenau, A; Stalker, J; Stupka, E; Ureta-Vidal, A; Vastrik, I; Clamp, M

Genomic strategies to identify mammalian regulatory sequences

NATURE REVIEWS GENETICS

IF52

2001-02-01

362

PREAI

Pennacchio, LA; Rubin, EM

The HUGO Gene Nomenclature Committee (HGNC)

HUMAN GENETICS

IF3.6

2001-10-24

391