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Genetic mutations and inhibitors of p300 and CBP
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DOI：10.1016/j.bbcan.2026.189599.png)
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Abstract
En 中文
• EP300 and CREBBP encode two homologous acetyltransferases p300 and CBP. • EP300 and CREBBP are relatively frequently mutated in cancers. • Some of p300/CBP inhibitors emerge promising in anticancer approaches. • Simultaneous mutations in EP300 and CREBBP may impact efficacy of p300/CBP inhibitors.
Keywords:
EP300
CREBBP
p300/CBP inhibitors
cancer mutations
acetyltransferases
Journal
B
IF:
0
Papers:
105
Citations:
0
Organization
Cited Papers