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Genetic overlap between depression and C-reactive protein levels: Evidence from a cross-trait analysis
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DOI：10.1016/j.euroneuro.2026.112901.png)
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Abstract
En 中文
• Genome-wide analysis identifies 9 novel loci shared by depression and CRP. • Concordant and discordant variants involve immune and metabolic pathways. • Body mass index mediates the causal effect of depression on CRP.
Keywords:
C-reactive protein
Depression
Body mass index
Genetic pleiotropy
Mendelian randomization analysis
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