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Genome editing

delete2022-11-28
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OA
AI
M
Maura McGrail *
T
Tetsushi Sakuma
L
Leonidas Bleris
DOI:10.1038/s41598-022-24850-xdelete
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摘要

摘要

En 中文
Recent advances in genome editing technologies have redefined our ability to probe and precisely edit the human genome and epigenome in vitro and in vivo. More specifically, RNA-guided CRISPR/Cas systems have revolutionized the field due to their simplicity in design and adaptability across biological systems. This Collection highlights results in CRISPR/Cas technology that increase the efficiency of precision genome editing, and allow genetic manipulation in model systems traditionally intractable to site-directed gene modification.
Keyword:
ONE-STEP GENERATION
DNA
CRISPR/CAS
GENES
CELLS
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期刊

Scientific Reports 封面图
Scientific Reports
IF:
3.9
论文数:
28.0W
被引数:
83.5W

机构

I
Iowa State University
学者数:
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论文数: 1.8W
被引数: 2.5W
U
university of texas system
学者数:
18.5W
论文数: 15.6W
被引数: 210
H
Hiroshima University
学者数:
2.1W
论文数: 1.5W
被引数: 1.3W
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