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Genomic Characterization of an ST44 Escherichia coli Isolate Harboring an mcr-8.2-Bearing IncR Plasmid from a Pediatric Patient in China
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DOI：10.1016/j.jgar.2026.05.002.png)
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Abstract
En 中文
• A transferable mcr-8.2-bearing IncR plasmid was identified in ST44 E. coli. • The plasmid mediated colistin reduced susceptibility and co-transferred aminoglycoside resistance. • Global phylogenetic analysis showed ST44 is not a common mcr reservoir. • The isolate carried virulence genes associated with invasive potential. • Pediatric intestinal microbiota may represent an under-recognized reservoir of mcr genes.
Keywords:
Escherichia coli
mcr-8
Pediatric infection
Plasmid-mediated resistance
Multidrug resistance
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