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HECTOR: Enabling Microarray Experiments over the Hellenic Grid Infrastructure
DOI:10.1007/s10723-009-9123-6.png)
摘要
En 中文
Biologists, medical experts, biochemical engineers and researchers working on DNA microarray experiments are increasingly turning on Grid computing with the scope of leveraging the Grid's computing power, immense storage resources, and quality of service to the expedient processing of a wide range of datasets. In this paper we present a combined experience of grid application experts and bioinformatics scientists in deploying a pilot service enabling computationally efficient processing and analysis of data stemming from microarray experiments. This pilot service is accessible over the Hellenic portion of the EGEE grid and has been demonstrated in the scope of several public events. We highlight the process of grid application enablement, grid deployment challenges, as well as lessons learnt from a bi-annual effort to port and deploy a MATLAB DNA microarray application on a production grid. In addition to describing the parallelization of the application, we also emphasize on the development of a distributed federated database for storing and post-processing the results of the microarray experiments. Overall we believe that our experience could be proven valuable not only to microarray data scientists but also to other Grid users that intend to Grid-enable and deploy their applications.
Keyword:
Grid application enablement
Microarray experiments
Hellas grid
EGEE
gLite
MPI
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期刊
IF:
2.9
论文数:
763
被引数:
1.2K
机构
引用论文
Minimum information about a microarray experiment (MIAME) - toward standards for microarray data微阵列实验的最低信息 (MIAME) -微阵列数据标准
NATURE GENETICS
IF31.8
Expression Profiler:: next generation-an online platform for analysis of microarray data
NUCLEIC ACIDS RESEARCH
IF13.1

