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Hematopoietic Clonal Evolution Goes Spatial
DOI:10.1158/2643-3230.BCD-24-0057.png)
摘要
En 中文
The spatial distribution of cells carrying clonal hematopoiesis mutations in the bone marrow and the potential role of interactions with the microenvironment are largely unknown. This study takes clonal evolution to the spatial level by describing a novel technique examining the spatial location of mutated clones in the bone marrow and the first evidence that mutated hematopoietic clones are spatially constrained and have heterogenous locations within millimeters of distance. See related article by Young et al., p. 153 (10).
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IF:
11.5
论文数:
216
被引数:
1.4K
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引用论文
The EBV oncogene LMP1 protects lymphoma cells from cell death through the collagen-mediated activation of DDR1
Blood
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