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Hematopoietic Clonal Evolution Goes Spatial

delete2024-05-01
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PRE
AI
R
Rebecca Austin
I
Iannis Aifantis *
DOI:10.1158/2643-3230.BCD-24-0057delete
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摘要

摘要

En 中文
The spatial distribution of cells carrying clonal hematopoiesis mutations in the bone marrow and the potential role of interactions with the microenvironment are largely unknown. This study takes clonal evolution to the spatial level by describing a novel technique examining the spatial location of mutated clones in the bone marrow and the first evidence that mutated hematopoietic clones are spatially constrained and have heterogenous locations within millimeters of distance. See related article by Young et al., p. 153 (10).

期刊

Blood Cancer Discovery 封面图
Blood Cancer Discovery
IF:
11.5
论文数:
216
被引数:
1.4K

机构

N
New York University
学者数:
4.4W
论文数: 3.9W
被引数: 5.8W
引用论文

引用论文

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