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'Profiles' of protein structures and sequence alignments can detect subtle homologies. Profile analysis has been put on firmer mathematical ground by the introduction of hidden Markov model (HMM) methods. During the past year, applications of these powerful new HMM-based profiles have begun to appear in the fields of protein-structure prediction and large-scale genome-sequence analysis.
Keyword:
PROTEIN
ALIGNMENT
SEQUENCES
DNA
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A TUTORIAL ON HIDDEN MARKOV-MODELS AND SELECTED APPLICATIONS IN SPEECH RECOGNITION关于语音识别中的隐马尔可夫模型和选定应用的教程.png)
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PROCEEDINGS OF THE IEEEIF25.9
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