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High-performance iterative electron tomography reconstruction with long-object compensation using graphics processing units (GPUs)

delete2010-08-01
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OA
AI
W
Wei Xu
F
Fang Xu
M
M.D. Jones
B
Bettina Keszthelyi
J
John W. Sedat
D
David A. Agard
K
Klaus Mueller *
DOI:10.1016/j.jsb.2010.03.018delete
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摘要

摘要

En 中文
Iterative reconstruction algorithms pose tremendous computational challenges for 3D Electron Tomography (ET). Similar to X-ray Computed Tomography (CT), graphics processing units (GPUs) offer an affordable platform to meet these demands. In this paper, we outline a CT reconstruction approach for ET that is optimized for the special demands and application setting of ET. It exploits the fact that ET is typically cast as a parallel-beam configuration, which allows the design of an efficient data management scheme, using a holistic sinogram-based representation. Our method produces speedups of about an order of magnitude over a previously proposed GPU-based Er implementation, on similar hardware, and completes an iterative 3D reconstruction of practical problem size within minutes. We also describe a novel GPU-amenable approach that effectively compensates for reconstruction errors resulting from the TEM data acquisition on (long) samples which extend the width of the parallel TEM beam. We show that the vignetting artifacts typically arising at the periphery of non-compensated ET reconstructions are completely eliminated when our method is employed. (C) 2010 Elsevier Inc. All rights reserved.
Keyword:
Tomography
Reconstruction
Image processing
Parallel processing

期刊

Journal of Structural Biology 封面图
Journal of Structural Biology
IF:
2.7
论文数:
4.4K
被引数:
1.0W

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stony brook university
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state university of new york (suny) system
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论文数: 5.8W
被引数: 65
University of California System 封面图
University of California System
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被引数: 6.6K
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