.png){kind=icon}
.png){kind=icon}
Return
Huang-Lian-Jie-Du Decoction alleviates cognitive deficits in Alzheimer’s disease via aromatase-mediated regulation of Aβ metabolism
.png){kind=icon}
PRE
AI
M
D
P
M
X
Y
L
Y
Z
G
DOI：10.1016/j.phymed.2026.158467.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and pathological accumulation of amyloid-β (Aβ). Hippocampal aromatase (AROM), a key enzyme for local estrogen biosynthesis, has emerged as an important regulator of Aβ metabolism. Huang-Lian-Jie-Du Decoction (HLJD), a classical traditional Chinese medicine formula, has shown therapeutic potential in AD; however, its molecular mechanism remains largely unclear.
Keywords:
HLJD
Alzheimer’s disease
Aromatase
Aβ homeostasis
Estrogen
Journal
IF:
8.3
Papers:
9.0K
Citations:
3.1W
Organization
Cited Papers