.png){kind=icon}
返回
Hyperthyroidism influences renal function
.png){kind=icon}
PRE
AI
DOI：10.1007/s12020-019-01903-2.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
PurposeWhile the effects of hypothyroidism on renal function have been studied extensively, there is less information concerning the effect of hyperthyroidism. We aimed to elucidate the effect of overt and subclinical hyperthyroidism, on estimated glomerular filtration rate (eGFR) with large number of patients treated for hyperthyroidism and after euthyroidism was achieved.MethodA total of 433 consecutive overt and subclinical hyperthyroid patients were included in the study. We assessed serum fT3, fT4, TSH, BUN, creatinine, and eGFR measurements during both hyperthyroid and euthyroid states of the same patients. The eGFR was calculated using the simplified modification of diet in renal disease (MDRD) Formula.ResultsAmong these patients, 367 had overt, and 66 had subclinical hyperthyroidism. fT3, fT4, and eGFR measurements decreased, meanwhile BUN, creatinine and TSH levels increased significantly after euthyroidism was achieved (p<0.0001 for all). The correlation analyses revealed that eGFR in hyperthyroid state (eGFRh) and fT3 in hyperthyroid state (fT3h) (r=0,210, p<0,0001), and fT4 in hyperthyroid state (fT4h) (r=0,176, p<0,0001) were significantly correlated. GFR did not differ between overt hyperthyroid group and subclinical hyperthyroid group.ConclusionsWe observed a significant decline in eGFR measurements after the patients became euthyroid. Some of these patients had lower values than 60mL/min/1.73m(2), which mean that hyperthyroidism may be masking mild renal failure.
Keyword:
eGFR
Creatinine
Hyperthyroidism
Renal function
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
2.9
论文数:
6.8K
被引数:
1.1W
机构
引用论文
A Review of the Effect of Reflective Surfaces on Power Output of Sound Sources and on Actively Created Quiet Zones反射表面对声源功率输出和主动创建的静音区的影响综述
.png){kind=icon}
PREAI
分享收藏Experimental study on vibration and sound radiation reduction of the web-mounted noise shielding and vibration damping wheel关于网架式噪声屏蔽与减振车轮的振动和声辐射减小的实验研究
PREAI
分享收藏
分享收藏分享收藏
查看更多内容