.png){kind=icon}
.png){kind=icon}
Return
Identification of Small-Molecule Autophagy Activators via GFP-LC3 High-Throughput Screening and a Cargo-Based Autophagy Flux and Processing Assay
.png){kind=icon}
PRE
AI
F
F
M
N
V
D
P
L
P
E
C
P
V
G
W
DOI：10.1016/j.ejphar.2026.178958.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• High-throughput screening identifies 30 novel autophagosome-increasing compounds • Ten compounds promote robust autophagic flux at levels similar to rapamycin • Nine compounds induce autophagy independently of the mTORC1 pathway • HTS-26 activates AMPK similarly to mTOR-independent reference compound metformin
Keywords:
autophagy activators
high-throughput screening
GFP-LC3
autophagic flux
AMPK activation
Journal
IF:
4.7
Papers:
2.3W
Citations:
4.0W
Organization
Cited Papers