.png){kind=icon}
返回
Image-Based Live Cell Sorting
.png){kind=icon}
OA
AI
DOI：10.1016/j.tibtech.2020.10.006.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Single-Cell Analysis and Sorting Paves the Way for Biomedical Breakthroughs The ability to analyze individual cells has revolutionized biomedical research and clinical medicine, leading to innovations that encompass genetic engineering, regenerative medicine, and cancer immunotherapies. While cell population data provide a wealth of information, there is an inherent loss of information from bulk cell samples. Small variations between adjacent cells are known to lead to profound physiologic differences, for example, immune cells vary in their ability to combat infection, neighboring hematopoietic stem cells differentiate into distinct cell lineages, and cancer Technologies capable of cell separation based on cell images provide powerful tools enabling cell selection criteria that rely on spatially or temporally varying properties. Image-based cell sorting (IBCS) systems utilize microfluidic or microarray platforms, each having unique characteristics and applications. The advent of IBCS marks a new paradigm in which cell phenotype and behavior can be explored with high resolution and tied to cellular physiological and omics data, providing a deeper understanding of single-cell physiology and the creation of cell lines with unique properties. Cell sorting guided by high-content image information has far-reaching implications in biomedical research, clinical medicine, and pharmaceutical development.
Keyword:
SINGLE CELLS
SELECTION
PLATFORM
IDENTIFICATION
MICROFLUIDICS
TECHNOLOGIES
CYTOMETRY
ARRAYS
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
14.9
论文数:
3.8K
被引数:
2.2W
机构
引用论文
Recent advances in microfluidic technologies for cell-to-cell interaction studies.png)
LAB ON A CHIPOAAI
LAB ON A CHIPIF5.4
OAAI分享收藏Automated platform for cell selection and separation based on four-dimensional motility and matrix degradationANALYSTOAAI
ANALYSTIF3.3
OAAI分享收藏Microraft array-based platform for sorting of viable microcolonies based on cell-lethal immunoassay of intracellular proteins in microcolony biopsiesANALYSTOAAI
ANALYSTIF3.3
OAAI分享收藏Automated sensing and splitting of stem cell colonies on microraft arraysAPL BIOENGINEERINGOAAI
APL BIOENGINEERINGIF4.1
OAAI分享收藏Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cellsNATURE COMMUNICATIONSOAAI
NATURE COMMUNICATIONSIF15.7
OAAI分享收藏Image-based sorting and negative dielectrophoresis for high purity cell and particle separationELECTROPHORESISOAAI
ELECTROPHORESISIF2.5
OAAI分享收藏
查看更多内容