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Imaging developmental cell cycles
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DOI：10.1016/j.bpj.2021.04.035.png)
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摘要
En 中文
The last decade has seen a major expansion in development of live biosensors, the tools needed to genetically encode them into model organisms, and the microscopic techniques used to visualize them. When combined, these offer us powerful tools with which to make fundamental discoveries about complex biological processes. In this review, we summarize the availability of biosensors to visualize an essential cellular process, the cell cycle, and the techniques for single-cell tracking and quantification of these reporters. We also highlight studies investigating the connection of cellular behavior to the cell cycle, particularly through live imaging, and anticipate exciting discoveries with the combination of these technologies in developmental contexts.
Keyword:
RESONANCE ENERGY-TRANSFER
STEM-CELL
TRANSCRIPTION FACTORS
SPATIOTEMPORAL DYNAMICS
RESTRICTION POINT
GENE-EXPRESSION
G1 PHASE
LINEAGE
PROGRESSION
MITOSIS
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对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
3.1
论文数:
5.1W
被引数:
4.4W
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