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Immunodomaince based Clonal Selection Clustering Algorithm
DOI:10.1016/j.asoc.2011.08.042.png)
摘要
En 中文
Based on clonal selection principle and the immunodominance theory, a new immune clustering algorithm, Immunodomaince based Clonal Selection Clustering Algorithm (ICSCA) is proposed in this paper. Firstly, by introducing a new immunodomaince operator to Clonal Selection Algorithm (CSA), the gene of elites in antibody population can be extracted and generalized to ordinary antibodies so as to gain on-line priori knowledge and share information among individuals. Then, one iteration of Fuzzy C-means clustering algorithm (FCM) and adaptive updating mechanism of antibody population are utilized to improve the diversity of antibody population in order to speed up the convergence speed. The proposed method has been extensively compared with FCM, GA-clustering algorithm (GACA) and Clonal Selection Algorithm based FCM (CSAFCM) over a test suit of several real life data sets and synthetic data sets. Experimental results indicate the superiority of the ICSCA over FCM, GAFCM and CSAFCM on clustering accuracy and robustness. (C) 2011 Elsevier B. V. All rights reserved.
Keyword:
Clone selection
Genetic algorithm
Immunodominance
Fuzzy clustering
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期刊
IF:
6.6
论文数:
1.4W
被引数:
4.8W
机构
引用论文
Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses主要组织相容性复合物I类限制性T淋巴细胞反应中的免疫优势

