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Immunosensor with self-referencing based on surface plasmon diffraction
DOI:10.1021/ac035369w.png)
摘要
En 中文
We propose a novel type of immunosensor based on the diffraction of surface plasmon, which allows for in situ, real-time, and label-free observation of interfacial binding events. The inherent self-referencing mechanism of surface diffraction was found to be very effective for compensating fluctuations of the bulk, demonstrated by a temperature variation experiment. Possessing a stable baseline signal, the diffraction sensor offered picomolar sensitivity in directly detecting the binding of human chorionic gonadotropin (hCG) hormone.
Keyword:
CELL
RECOGNITION
BIOSENSOR
ANTIBODY
ASSAY
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期刊
IF:
6.7
论文数:
4.7W
被引数:
15.9W
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引用论文
Temperature-dependent refractive index determination from critical angle measurements: Implications for quantitative SPR sensing
ANALYTICAL CHEMISTRY
IF6.7
Surface functionalization for self-referencing surface plasmon resonance (SPR) biosensors by multi-step self-assembly通过多步自组装实现自参考表面等离子体共振 (SPR) 生物传感器的表面功能化
Porogen residues detection in optical properties of low-k dielectrics cured by ultraviolet radiation

