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Impact of Acute Graft-Versus-Host Disease and Delayed Hematopoietic Recovery on the Incidence and Clinical Burden of Late Cytomegalovirus Reactivation and Disease After Letermovir Prophylaxis During the First 100 Days After Cord Blood Transplantation
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DOI：10.1016/j.jtct.2026.06.020.png)
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Abstract
En 中文
• Large cohort of late CMV reactivation and disease after LTV prophylaxis in CBT. • Late CMV reactivation was frequent, with a 1-year cumulative incidence of 47.9%. • Acute GVHD and delayed hematopoietic recovery increase late CMV reactivation/disease. • These risk factors also increase the clinical burden of CMV management. • Extended LTV prophylaxis is recommended for CBT and essential for high-risk cases.
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