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Improved ASD classification using dynamic functional connectivity and multi-task feature selection

delete2020-10-01
delete45
PRE
AI
J
Jin Liu
Y
Yu Sheng
W
Wei Lan
R
Rui Guo
Y
Yufei Wang
王健行 封面图
王健行 (Jianxin Wang) *
DOI:10.1016/j.patrec.2020.07.005delete
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摘要

摘要

En 中文
Accurate diagnosis of autism spectrum disorder (ASD), which is a neurodevelopmental disorder and often accompanied by abnormal social skills, communication skills, interests and behavior patterns, has always been a challenging task in clinical practice. Recent studies have shown great potential for using fMRI data to distinguish ASD from typical control (TC). However, it has always been a challenging problem to extract which features from fMRI data and how to combine these different types of features to achieve improved ASD/TC classification performance. To address this problem, in this study we propose an improved ASD/TC classification framework based on dynamic functional connectivity (DFC) and multi-task feature selection. Our proposed ASD/TC classification framework is evaluated on 871 subjects with fMRI data from the Autism Brain Imaging Data Exchange I (ABIDE I) via a 10-fold cross validation strategy. Experimental results show that our proposed method achieves an accuracy of 76.8% and an area under the receiver operating characteristic curve (AUC) of 0.81 for ASD/TC classification. In addition, compared with some existing state-of-the-art methods, our proposed method achieves better accuracy and AUC for ASD/TC classification. Overall, our proposed ASD/TC classification framework is effective and promising for automatic diagnosis of ASD in clinical practice. (C) 2020 Elsevier B.V. All rights reserved.
Keyword:
ASD Classification
Resting state functional MRI
Dynamic functional connectivity
Multi-task feature selection
Multi-kernel learning
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期刊

Pattern Recognition Letters 封面图
Pattern Recognition Letters
IF:
3.3
论文数:
7.9K
被引数:
1.6W

机构

C
Central South University
学者数:
10.0W
论文数: 7.2W
被引数: 10.9W
G
guangxi university
学者数:
3.4W
论文数: 1.8W
被引数: 25
引用论文

引用论文

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