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Improved ASD classification using dynamic functional connectivity and multi-task feature selection
DOI:10.1016/j.patrec.2020.07.005.png)
摘要
En 中文
Accurate diagnosis of autism spectrum disorder (ASD), which is a neurodevelopmental disorder and often accompanied by abnormal social skills, communication skills, interests and behavior patterns, has always been a challenging task in clinical practice. Recent studies have shown great potential for using fMRI data to distinguish ASD from typical control (TC). However, it has always been a challenging problem to extract which features from fMRI data and how to combine these different types of features to achieve improved ASD/TC classification performance. To address this problem, in this study we propose an improved ASD/TC classification framework based on dynamic functional connectivity (DFC) and multi-task feature selection. Our proposed ASD/TC classification framework is evaluated on 871 subjects with fMRI data from the Autism Brain Imaging Data Exchange I (ABIDE I) via a 10-fold cross validation strategy. Experimental results show that our proposed method achieves an accuracy of 76.8% and an area under the receiver operating characteristic curve (AUC) of 0.81 for ASD/TC classification. In addition, compared with some existing state-of-the-art methods, our proposed method achieves better accuracy and AUC for ASD/TC classification. Overall, our proposed ASD/TC classification framework is effective and promising for automatic diagnosis of ASD in clinical practice. (C) 2020 Elsevier B.V. All rights reserved.
Keyword:
ASD Classification
Resting state functional MRI
Dynamic functional connectivity
Multi-task feature selection
Multi-kernel learning
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期刊
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3.3
论文数:
7.9K
被引数:
1.6W
机构
引用论文
Enhancing the feature representation of multi-modal MRI data by combining multi-view information for MCI classification
NEUROCOMPUTING
IF6.5
Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 20148岁儿童中自闭症谱系障碍的患病率-自闭症和发育障碍监测网络,11个站点,美国,2014

