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In silico selection and in vivo evaluation of scoloptoxin SSD14, Rm-inositol monophosphatase, and Rm-neprilysin as potential anti-tick vaccines
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DOI：10.1016/j.vaccine.2026.128789.png)
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Abstract
En 中文
• In silico selection identified three protective tick antigens. • Rm-Neprilysin achieved 64% efficacy against R. linnaei. • Rm-IMP decreased adult female ticks by 22% (58% overall). • Rm-SSD reduced egg fertility by 37% (47% overall). • These proteins are promising for anti-tick cocktail vaccines.
Keywords:
Antigens
Anti-tick vaccine
Rabbits
Adjuvant
Rhipicephalus microplus
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