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Inductive Materials for Regenerative Engineering

delete2021-04-27
delete13
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OA
AI
F
Fatemeh S. Hosseini
L
Lakshmi S. Nair
C
Cato T. Laurencin *
DOI:10.1177/00220345211010436delete
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Abstract

Abstract

En 中文
Regenerative engineering has pioneered several novel biomaterials to treat critical-sized bone injuries. However, despite significant improvement in synthetic materials research, some limitations still exist. The constraints correlated with the current grafting methods signify a treatment paradigm shift to osteoinductive regenerative engineering approaches. Because of their intrinsic potential, inductive biomaterials may represent alternative approaches to treating critical bone injuries. Osteoinductive scaffolds stimulate stem cell differentiation into the osteoblastic lineage, enhancing bone regeneration. Inductive biomaterials comprise polymers, calcium phosphate ceramics, metals, and graphene family materials. This review will assess the cellular behavior toward properties of inductive materials.
Keywords:
biomaterials
osteoinductive
bone regeneration
stem cell
graphene
osteoblast differentiation
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Journal

Journal of Dental Research cover
Journal of Dental Research
IF:
5.9
Papers:
6.0K
Citations:
2.5W

Organization

U
University of Connecticut
Scholars:
2.4W
Papers: 2.2W
Citations: 2.5W