.png){kind=icon}
返回
Integrated microspectrometer for fluorescence based analysis in a microfluidic format
.png){kind=icon}
PRE
AI
DOI：10.1039/c2lc40169j.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
We have demonstrated a monolithic integrated arrayed waveguide grating (AWG) microspectrometer microfluidic platform capable of fluorescence spectroscopic analysis. The microspectrometer in this proof of concept study has a small (1 cm x 1 cm) footprint and 8 output channels centred on different wavelengths. We show that the signals from the output channels detected on a camera chip can be used to recreate the complete fluorescence spectrum of an analyte. By making fluorescence measurements of (i) mixed quantum dot solutions, (ii) an organic fluorophore (Cy5) and (iii) the propidium iodide (PI)-DNA assay, we illustrate the unique advantages of the AWG platform for simultaneous, quantitative multiplex detection and its capability to detect small spectroscopic shifts. Although the current system is designed for fluorescence spectroscopic analysis, in principle, it can be implemented for other types of analysis, such as Raman spectroscopy. Fabricated using established semiconductor industry methods, this miniaturised platform holds great potential to create a handheld, low cost biosensor with versatile detection capability.
Keyword:
WAVE-GUIDES
SILICON
DESIGN
DNA
TECHNOLOGIES
FABRICATION
BIOSENSORS
PROPIDIUM
DEVICES
BIOCHIP
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
L
IF:
5.4
论文数:
9.0K
被引数:
3.3W
机构
引用论文
Optimizing the deposition of CdSe colloidal quantum dots on TiO2film electrode via capping ligand induced self-assembly approach.png)
RSC Advances
RSC AdvancesIF0
PREAI
分享收藏
Integrated microfluidic biophotonic chip for laser induced fluorescence detection用于激光诱导荧光检测的集成微流控生物光子芯片
PREAI
分享收藏
查看更多内容