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Interplay between growth factor signaling and epigenetic landscapes in stem cell stemness
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DOI:10.1016/j.cyto.2026.157188.png)
Abstract
En 中文
• Growth factors/cytokines affect ESC/ASCs stemness via signal-epigenomic interplay. • LIF, Wnt, Notch, BMP4, FGF2, TGF-β control contextual self-renewal/differentiation. • Epigenetic biases integrate signals for hierarchical stem cell fate control. • Spatiotemporal signal evolution from ESCs to ASCs informs regenerative therapies.
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