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INTRANASAL FLUNISOLIDE TREATMENT IN PATIENTS WITH NON-ALLERGIC RHINITIS

delete2011-04-01
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OA
AI
A
Attilio Varricchio
M
Michele Capasso
A
Andrea De Lucia
A
Avvisati, F.
G
Germano Bettoncelli
G
Giorgio Ciprandi
DOI:10.1177/039463201102400213delete
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Abstract

Abstract

En 中文
Non-allergic rhinitis (NAR) is a heterogeneous disease, characterized by nasal hyperreactivity and inflammation. Its treatment is still debated, intranasal corticosteroids may be an option. The present study is aimed at evaluating the effect of the use of intranasal flunisolide in patients with NAR, considering both clinical and cytological parameters. Sixty patients were treated with intranasal flunisolide (30) or saline solution (30) for 8 weeks. Symptom severity, turbinate size, and inflammatory cell counts were assessed, before and after treatment. lntranasal flunisolide induced a significant reduction of symptoms, turbinate size, and cellular infiltrate. Thus, intranasal flunisolide might be a therapeutic option for NAR.
Keywords:
intranasal corticosteroids
intranasal flunisolide
non-allergic rhinitis
inflammatory cells
turbinates
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Journal

I
International Journal of Immunopathology and Pharmacology
IF:
2.6
Papers:
2.3K
Citations:
3.1K

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irccs aou san martino ist
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3.5K
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Citations: 3
U
university of genoa
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Papers: 2.2W
Citations: 20
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