Label-free bioaffinity detection using terahertz technology

Samuel P. Mickan

doi:10.1088/0031-9155/47/21/317

2002-10-16

156

DOI：10.1088/0031-9155/47/21/317

原文链接

摘要

En 中文

We report the first use of differential terahertz time-domain spectroscopy for bioaffinity sensing. Binding is observed by measuring the transmission of a thin layer of biotin bound to the sensor protein avidin. We demonstrate the THz wave transmission of a sub-micron-thick film and sensitivity to 0.1 mug cm(-2) of biotin. These results point the way for a host of biosensor applications using T-rays, or pulsed far-infrared (FIR) radiation.

Keyword:

IMMOBILIZATION

AVIDIN

期刊

Physics in Medicine and Biology

IF:

3.4

论文数:

1.4W

被引数:

3.1W

机构

暂无机构信息

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