.png){kind=icon}
返回
Label-free fiber optic biosensor based on thin-core modal interferometer
.png){kind=icon}
OA
AI
DOI：10.1016/j.snb.2016.01.029.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
A label-free, cost-effective fiber optic biosensor (FOB) using electrostatic self-assembly (ESA) technology is presented and experimentally demonstrated. The FOB was constructed by sandwiching a thin-core single-mode fiber (TCSMF) between two single-mode fibers (SMFs). Firstly, we simulated the refractive index (RI) sensitivity of this fiber structure, and validated it using different concentrations of glycerol solutions. Then the diallyldimethyl ammonium chloride (PDDA) and styrenesulfonate sodium salt (PSS) were employed as polyelectrolyte self-assembled multilayers (PSAMs) deposition for surface functionalization of the fiber. We selected biotin-streptavidin as a bioconjugate pair for testing the effectiveness of the biosensor, and achieved a streptavidin detection limit of 0.02 nM. The specificity was further verified by a comparison experiment conducted using bovine serum albumin (BSA) and gelatin. These results demonstrate the feasibility of this sensor for use in biological and chemical applications. (C) 2016 Elsevier B.V. All rights reserved.
Keyword:
Thin-core single-mode fiber
Fiber optic biosensor
Polyelectrolyte self-assembled multilayers
Biotin-streptavidin
Specifity
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
7.7
论文数:
3.4W
被引数:
12.6W
机构
引用论文
分享收藏Low-cost high-performance fiber-optic pH sensor based on thin-core fiber modal interferometer.png)
OPTICS EXPRESS
OAAI
OPTICS EXPRESSIF3.3
OAAI分享收藏Single mode tapered fiber-optic interferometer based refractive index sensor and its application to protein sensingOPTICS EXPRESSOAAI
OPTICS EXPRESSIF3.3
OAAI分享收藏
查看更多内容