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Lactylation-Related Genes in Ulcerative Colitis: A Multiomics Mendelian Randomization Study for Therapeutic Target Discovery

delete2026-06-26
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OA
AI
N
Na An
R
Ruiyun Wang
H
Huiping Jiao
Z
Zhongwen Lu
Y
Yafei Dou
L
Laikun Zheng
Z
Zhaoliang Ding *
DOI:10.1155/humu/7720538delete
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Abstract

Abstract

En 中文
Ulcerative colitis (UC), a chronic and nonspecific intestinal inflammatory disease, has seen a rising incidence rate worldwide year by year. Its pathogenesis remains incompletely understood. Lactylation modification is closely related to the generation of inflammation. Exploring the pathogenesis of UC from the perspective of lactylation is of great significance for the understanding and treatment of UC.
Keywords:
lactylation
Mendelian randomization
multiomics integration
qPCR
spatial transcriptome
ulcerative colitis
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Human Mutation cover
Human Mutation
IF:
3.7
Papers:
5.1K
Citations:
1.3W

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shandong university of traditional chinese medicine
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1.3K
Papers: 410
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R
Rizhao Hospital of Traditional Chinese Medicine
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10
Papers: 4
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