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Landmark-modulated directional coding in postrhinal cortex
DOI:10.1126/sciadv.abg8404.png)
摘要
En 中文
Visual landmarks can anchor an animal's internal sense of orientation to the external world. The rodent postrhinal cortex (POR) may facilitate this processing. Here, we demonstrate that, in contrast to classic head direction (HD) cells, which have a single preferred orientation, POR HD cells develop a second preferred orientation when an established landmark cue is duplicated along another environmental wall. We therefore refer to these cells as landmark--modulated-HD (LM-HD) cells. LM-HD cells discriminate between landmarks in familiar and novel locations, discriminate between visually disparate landmarks, and continue to respond to the previous location of a familiar landmark following its removal. Rats initially exposed to different stable landmark configurations show LM-HD tuning that may reflect the integration of visual landmark information into an allocentric HD signal. These results provide insight into how visual landmarks are integrated into a framework that supports the neural encoding of landmark--based orientation.
Keyword:
FREELY MOVING RATS
HEAD-DIRECTION
ENTORHINAL CORTICES
FIRING PROPERTIES
CELLS
HIPPOCAMPAL
REPRESENTATION
POSTSUBICULUM
INFORMATION
DISCRIMINATION
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期刊
IF:
12.5
论文数:
2.1W
被引数:
18.1W
机构
引用论文
Intermingled Ensembles in Visual Association Cortex Encode Stimulus Identity or Predicted Outcome
NEURON
IF15
Dissociation between Postrhinal Cortex and Downstream Parahippocampal Regions in the Representation of Egocentric Boundaries
CURRENT BIOLOGY
IF7.5

