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Light-Patterned Current Generation in a Droplet Bilayer Array
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DOI：10.1038/srep46585.png)
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摘要
En 中文
We have created a 4 x 4 droplet bilayer array comprising light-activatable aqueous droplet bio-pixels. Aqueous droplets containing bacteriorhodopsin (bR), a light-driven proton pump, were arranged on a common hydrogel surface in lipid-containing oil. A separate lipid bilayer formed at the interface between each droplet and the hydrogel; each bilayer then incorporated bR. Electrodes in each droplet simultaneously measured the light-driven proton-pumping activities of each bio-pixel. The 4 x 4 array derived by this bottom-up synthetic biology approach can detect grey-scale images and patterns of light moving across the device, which are transduced as electrical current generated in each bio-pixel. We propose that synthetic biological light-activatable arrays, produced with soft materials, might be interfaced with living tissues to stimulate neuronal pathways.
Keyword:
IMAGE DETECTION
BACTERIORHODOPSIN
PROTEIN
MEMBRANE
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3.9
论文数:
27.9W
被引数:
83.5W
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OAAI分享收藏Enhanced stability and fluidity in droplet on hydrogel bilayers for measuring membrane protein diffusionNANO LETTERS
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