.png){kind=icon}
返回
Liver Sinusoidal Endothelial Cells
.png){kind=icon}
OA
AI
DOI：10.1002/cphy.c140078.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
The liver sinusoidal endothelial cell (LSEC) forms the fenestrated wall of the hepatic sinusoid and functions as a control post regulating and surveying the trafficking of molecules and cells between the liver parenchyma and the blood. The cell acts as a scavenger cell responsible for removal of potential dangerous macromolecules from blood, and is increasingly acknowledged as an important player in liver immunity. This review provides an update of the major functions of the LSEC, including its role in plasma ultrafiltration and regulation of the hepatic microcirculation, scavenger functions, immune functions, and role in liver aging, as well as issues that are either undercommunicated or confusingly dealt with in the literature. These include metabolic functions, including energy metabolic interplay between the LSEC and the hepatocyte, and adequate ways of identifying and distinguishing the cells. (C) 2015 American Physiological Society.
Keyword:
RECEPTOR-MEDIATED ENDOCYTOSIS
LOW-DENSITY-LIPOPROTEIN
AGE-RELATED-CHANGES
GLYCATION END-PRODUCTS
HEPATIC MICROVASCULAR INJURY
FC-GAMMA-RIIB
PATTERN-RECOGNITION RECEPTORS
ANTIGEN-ANTIBODY COMPLEXES
RAT-LIVER
MANNOSE RECEPTOR
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
5.2
论文数:
953
被引数:
8.4K
机构
引用论文
Purification, properties and partial amino-acid sequence of 1-aminocyclopropane-1-carboxylic acid oxidase from apple fruits.png)
Planta
PlantaIF0
PREAI
分享收藏
The properties of a glass polyalkenoate (ionomer) cement incorporating sintered metallic particles
PREAI
分享收藏分享收藏
查看更多内容