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Longitudinal, prospective evaluation of inflammatory tear cytokine ratios and their association with ocular surface disease

delete2026-08-03
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OA
AI
R
Rachel K. Casemore *
J
James S. Wolffsohn
T
Tor Paaske Utheim
S
Sjur Reppe
H
Hans Christian D. Aass
D
Debarun Dutta
DOI:10.1016/j.jtos.2026.08.001delete
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Abstract

Abstract

En 中文
• Ocular surface disease and meibomian gland loss present in young adults regardless of dry eye status. • Upregulation of both pro- and anti-inflammatory cytokines present early in the development of DED. • Upregulation of anti-inflammatory cytokines reflects immune response to maintain homeostasis. • Longitudinal correlation of anti-to pro-inflammatory cytokine ratio with ocular redness.
Keywords:
Tear cytokines
Cytokine ratio
Anti-inflammatory
Pro-inflammatory
Evaporative dry eye disease
Young adults
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Ocular Surface cover
Ocular Surface
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5.6
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Aston University
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O
Oslo University Hospital
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