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Lung cancer screening
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DOI：10.1016/S0140-6736(22)01694-4.png)
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摘要
En 中文
Randomised controlled trials, including the National Lung Screening Trial (NLST) and the NELSON trial, have shown reduced mortality with lung cancer screening with low-dose CT compared with chest radiography or no screening. Although research has provided clarity on key issues of lung cancer screening, uncertainty remains about aspects that might be critical to optimise clinical effectiveness and cost-effectiveness. This Review brings together current evidence on lung cancer screening, including an overview of clinical trials, considerations regarding the identification of individuals who benefit from lung cancer screening, management of screen-detected findings, smoking cessation interventions, cost-effectiveness, the role of artificial intelligence and biomarkers, and current challenges, solutions, and oppor tunities surrounding the implementation of lung cancer screening programmes from an international perspective. Further research into risk models for patient selection, personalised screening intervals, novel biomarkers, inte grated cardiovascular disease and chronic obstructive pulmonary disease assessments, smoking cessation inter ventions, and artificial intelligence for lung nodule de tection and risk stratification are key opportunities to increase the efficiency of lung cancer screening and ensure equity of access.
Keyword:
LOW-DOSE CT
AIR-FLOW OBSTRUCTION
COMPUTED-TOMOGRAPHY
COST-EFFECTIVENESS
SMOKING-CESSATION
HIGH-RISK
PULMONARY NODULES
INCIDENTAL FINDINGS
NEVER-SMOKERS
PRIMARY-CARE
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对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
88.5
论文数:
5.4W
被引数:
34.8W
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引用论文
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Lung Cancer Screening and Smoking Cessation Clinical Trials SCALE (Smoking Cessation within the Context of Lung Cancer Screening) Collaboration肺癌筛查和戒烟临床试验量表 (肺癌筛查背景下的戒烟) 合作OAAI
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