.png){kind=icon}
返回
Lung function in men with and without HIV
.png){kind=icon}
OA
AI
DOI：10.1097/QAD.0000000000002526.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Objectives: Initial studies suggest HIV-positive persons may be at increased risk for chronic lung diseases such as chronic obstructive pulmonary disease, but have commonly relied on single-center designs, lacked HIV-negative controls, or assessed lung function with only spirometry. We tested differences in spirometry and single-breath diffusing capacity for carbon monoxide (DLCO) in persons with and without HIV. Design: Cross-sectional, observational study. Methods: Participants were enrolled from the Multicenter AIDS Cohort Study, a longitudinal cohort study of men who have sex with men (both HIV-positive and HIV-negative) at four sites in the United States. Standardized spirometry and DL(CO)testing were performed in all eligible, consenting participants at routine study visits. We tested associations between HIV status and spirometry and DL(CO)results, using linear and logistic regression. Results: Among 1067 men, median age was 57 years, prevalence of current marijuana (30%), and cigarette (24%) use was high, and another 45% were former cigarette smokers. Median forced expiratory volume in 1 s was 97% of predicted normal and DL(CO)was 85% of predicted normal. HIV-positive persons demonstrated no statistical difference in forced expiratory volume in 1 s compared with HIV-negative persons, but had worse DLCO(adjusted difference -2.6% of predicted; 95% confidence interval: -4.7 to -0.6%) and a higher risk of DL(CO)impairment (odds ratio for DLCO < 60% of predicted 2.97; 95% confidence interval: 1.36-6.47). Lower DL(CO)was associated with lower nadir CD4(+)cell counts. Conclusion: HIV-positive men are at increased risk of abnormal gas exchange, indicated by low DLCO, compared with men without HIV.
Keyword:
chronic obstructive
HIV
pulmonary disease
pulmonary gas exchange
respiratory function tests
spirometry
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
3.1
论文数:
1.2W
被引数:
1.4W
机构
引用论文
分享收藏Wave-Tacotron: Spectrogram-Free End-to-End Text-to-Speech Synthesis.png)
ICASSP 2021 - 2021 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)OAAI
ICASSP 2021 - 2021 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)IF0
OAAI分享收藏Per cent emphysema is associated with respiratory and lung cancer mortality in the general population: a cohort study在普通人群中，肺气肿百分比与呼吸道和肺癌死亡率相关: 一项队列研究THORAXOAAI
THORAXIF7.7
OAAI分享收藏
查看更多内容