Managing Hemostasis in Space

doi:10.1161/ATVBAHA.123.318783

2023-11-01

PRE

Nathan J. White *

DOI：10.1161/ATVBAHA.123.318783

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摘要

En 中文

Human space travel requires exposure to weightlessness, ionizing radiation, isolation, and austerity. A recent report of internal jugular vein thrombosis in astronauts in low Earth orbit confirms that these exposures also affect vascular biology to influence diseases of thrombosis and hemostasis. This brief review summarizes the known influences of space travel on inflammation, blood coagulation, and the cardiovascular system and conceptualizes how they might combine to affect thrombosis and hemostasis. In the event of a major thrombotic or bleeding emergency, it is anticipated that the unique physiological influences of the space environment and logistical limitations of providing medical care in space would require a response that is unique from our current experience. We also look towards the future to discuss lessons learned from our current experiences on Earth and in space.

Keyword:

astronauts

hemostasis

inflammation

space flight

thrombosis

期刊

Arteriosclerosis Thrombosis and Vascular Biology

IF:

7.4

论文数:

1.2W

被引数:

3.5W

机构

Harborview Medical Center

学者数:

1.4K

论文数: 1.1K

被引数: 1.2K

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