Maternal Immunization

Denise J. Jamieson

doi:10.1097/aog.0000000000006243

2026-05-01

PRE

Denise J. Jamieson *

Munoz, Flor M.

Sonja A. Rasmussen

DOI：10.1097/aog.0000000000006243

原文链接

摘要

En 中文

孕妇在孕期接种的疫苗可为母亲、胎儿或两者提供对严重传染病的保护。母体免疫接种可提高母体抗体浓度，这些抗体可通过胎盘转移，直接保护无法接种疫苗的婴幼儿。此外，通过预防母体感染和母乳抗体，母体免疫接种还可实现间接保护。总体而言，灭活疫苗被认为对孕妇和胎儿是安全的，而活减毒疫苗则因存在感染胎儿的潜在理论风险而避免使用。然而，疫苗的潜在风险需要与疾病本身的风险以及保护母婴免受传染病侵害的疫苗接种益处进行权衡。破伤风类毒素、减量白喉类毒素和无细胞百日咳（Tdap）、流感、2019冠状病毒病（COVID-19）以及呼吸道合胞病毒（RSV）疫苗在美国均被常规推荐给所有孕妇接种。母体免疫接种有潜力改善母婴健康；因此，在此期间具有相关性的其他疾病，如B群链球菌（GBS），已成为积极研究和疫苗开发的目标。同样，在特殊情况下（如母体健康、旅行或其他特殊情况），也可在孕期接种某些疫苗。本文回顾了当前关于孕期妇女疫苗接种的建议。

Keyword:

RESPIRATORY SYNCYTIAL VIRUS

GROUP-B STREPTOCOCCUS

INACTIVATED INFLUENZA VACCINE

ACELLULAR PERTUSSIS VACCINES

YELLOW-FEVER VACCINATION

AGED 19-59 YEARS

ADVISORY-COMMITTEE

PREGNANT-WOMEN

UNITED-STATES

UPDATED RECOMMENDATIONS

期刊

Obstetrics and Gynecology

IF:

4.7

论文数:

1.8W

被引数:

3.8W

机构

University of Iowa

学者数:

1.0K

论文数: 377

被引数: 436

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