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Mechanical signature of cancer cells: From cytoskeletal alterations to cell rheology
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DOI:10.1016/j.pbiomolbio.2026.05.001.png)
Abstract
En 中文
• Cytoskeletal remodeling links EMT to cancer cell mechanical phenotypes. • Quantifies elasticity and viscoelasticity using AFM, tweezers, and microfluidics. • Compares rheological models (power-law, SLS, Maxwell) for parameter extraction. • Summarizes benchmark values across methods in tables and supplementary data. • Outlines standardization needs to translate mechanical signatures into biomarkers.
Keywords:
cytoskeletal remodeling
cancer cell mechanics
rheological modeling
atomic force microscopy
viscoelasticity
Journal
IF:
4.5
Papers:
1.8K
Citations:
4.7K
