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Methodological Challenges in Online Trials

delete2009-04-03
delete159
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OA
AI
E
Elizabeth Murray *
K
Khadjesari, Zamie
I
Ian R. White
E
Eleftheria Kalaitzaki
C
Christine Godfrey
J
Jim McCambridge
S
Simon G. Thompson
P
Paul Wallace
DOI:10.2196/jmir.1052delete
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摘要

摘要

En 中文
Health care and health care services are increasingly being delivered over the Internet. There is a strong argument that interventions delivered online should also be evaluated online to maximize the trial's external validity. Conducting a trial online can help reduce research costs and improve some aspects of internal validity. To date, there are relatively few trials of health interventions that have been conducted entirely online. In this paper we describe the major methodological issues that arise in trials (recruitment, randomization, fidelity of the intervention, retention, and data quality), consider how the online context affects these issues, and use our experience of one online trial evaluating an intervention to help hazardous drinkers drink less (DownYourDrink) to illustrate potential solutions. Further work is needed to develop online trial methodology.
Keyword:
Internet
randomized controlled trial
research design
alcohol drinking

期刊

Journal of Medical Internet Research 封面图
Journal of Medical Internet Research
IF:
6
论文数:
9.7K
被引数:
5.0W

机构

M
medical research council uk (mrc)
学者数:
2.1K
论文数: 1.4K
被引数: 2
U
University College London
学者数:
7.9W
论文数: 6.2W
被引数: 15.7W
M
MRC Biostatistics Unit
学者数:
775
论文数: 788
被引数: 3.6K
U
uk research & innovation (ukri)
学者数:
2.7W
论文数: 2.3W
被引数: 32
U
university of london
学者数:
21.5W
论文数: 19.7W
被引数: 305
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