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Microbial sensor cell arrays

delete2012-02-01
delete53
PRE
AI
S
Sahar Melamed
T
Tal Elad
S
Shimshon Belkin *
DOI：10.1016/j.copbio.2011.11.024delete
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摘要

摘要

En 中文
Motivated by the advantages endowed by high-throughput analysis, researchers have succeeded in incorporating multiple reporter cells into a single platform; the technology now allows the simultaneous scrutiny of a large collection of sensor strains. We review current aspects in cell array technology with emphasis on microbial sensor arrays. We consider various techniques for patterning live cells on solid surfaces, describe different array-based applications and devices, and highlight recent efforts for live cell storage. We review mathematical approaches for deciphering the data emanating from bioreporter collections, and discuss the future of single cell arrays. Innovative technologies for cell patterning, preservation and interpretation are continuously being developed; when they all mature, cell arrays may become an efficient analytical tool, in a scope resembling that of DNA microarray biochips.
Keyword:
GENE-EXPRESSION
BACTERIA
IDENTIFICATION
RESPONSES
ARSENITE
DENSITY
DESIGN
PANEL
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期刊

Current Opinion in Biotechnology 封面图
Current Opinion in Biotechnology
IF:
7
论文数:
4.9K
被引数:
1.9W

机构

H
Hebrew University of Jerusalem
学者数:
2.8W
论文数: 2.3W
被引数: 2.7W
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