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Microfabricated rubber microscope using soft solid immersion lenses

delete2006-04-24
delete34
PRE
AI
Y
Yann Gambin
O
Olivier Legrand
Q
Quake, SR
DOI:10.1063/1.2194477delete
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摘要

摘要

En 中文
We show here a technique of soft lithography to microfabricate efficient solid immersion lenses (SIL) out of rubber elastomers. The light collection efficiency of a lens system is described by its numerical aperture (NA), and is critical for applications as epifluorescence microscopy [B. Herman, Fluorescence Microscopy (BIOS Scientific, Oxford/Springer, United Kingdom, 1998). While most simple lens systems have numerical apertures less than 1, the lenses described here have NA=1.25. Better performance can be engineered though the use of compound designs; we used this principle to make compound solid immersion lenses (NA=1.32). An important application of these lenses will be as integrated optics for microfluidic devices. We incorporated them into a handheld rubber microscope for microfluidic flow cytometry and imaged single E. Coli cells by fluorescence. (c) 2006 American Institute of Physics.
Keyword:
LITHOGRAPHY
STORAGE
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期刊

Applied Physics Letters 封面图
Applied Physics Letters
IF:
3.6
论文数:
10.4W
被引数:
17.8W

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