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MicroRNAs in Memory Processing

delete2009-09-01
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OA
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Soren Fischbach
T
Thomas Carew *
DOI:10.1016/j.neuron.2009.09.007delete
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摘要

摘要

En 中文
MicroRNAs are a class of small RNA molecules that regulate the expression of a wide variety of genes. In this issue of Neuron, Rajasethupathy and colleagues identify 170 distinct microRNAs in Aplysia, including one, miR-124, that plays a critical role in the regulation of signaling molecules underlying synaptic plasticity and memory.
Keyword:
LONG-TERM FACILITATION
PROTEIN-KINASE
APLYSIA
INHIBITION
MECHANISMS
ENCODES
MIRNAS

期刊

Neuron 封面图
Neuron
IF:
15
论文数:
1.4W
被引数:
9.9W

机构

University of California System 封面图
University of California System
学者数:
37.7W
论文数: 33.8W
被引数: 6.6K
引用论文

引用论文

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Characterization of Small RNAs in Aplysia Reveals a Role for miR-124 in Constraining Synaptic Plasticity through CREB
errNEURON
IF15
err2009-09-01
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errOAAI
errRajasethupathy, Priyamvada; Fiumara, Ferdinando; Sheridan, Robert; Betel, Doron; Puthanveettil, Sathyanarayanan V.; Russo, James J.; Sander, Chris; Tuschl, Thomas; Kandel, Eric
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MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia
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errMartin, KC; Michael, D; Rose, JC; Barad, M; Casadio, A; Zhu, HX; Kandel, ER
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The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative Pre-mRNA splicing
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Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia
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IF15
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errChain, DG; Casadio, A; Schacher, S; Hegde, AN; Valbrun, M; Yamamoto, N; Goldberg, AL; Bartsch, D; Kandel, ER; Schwartz, JH
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