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Mitochondrial uncoupling therapy reduces established atherosclerosis in mice
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DOI：10.1038/s41569-026-01330-7.png)
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Abstract
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Targeting systemic metabolism through mild mitochondrial uncoupling with a controlled-release mitochondrial protonophore can reduce atherosclerosis in a mouse model of cardiometabolic syndrome, even when administered at late stages of disease progression.
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