Modeling Protein Aggregation Kinetics from NMR Data

doi:10.1016/j.jmb.2025.169269

2025-06-09

PRE

DOI：10.1016/j.jmb.2025.169269

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摘要

En 中文

• 核磁共振（NMR）在监测蛋白质纤维化过程及其动力学建模方面的应用进行了描述。 • 提供了蛋白质聚集动力学理论基础的简要概述。 • 对源自核磁共振（NMR）数据的致病性亨廷顿外显子-1蛋白聚集动力学建模进行了描述。 • 使用核磁共振（NMR）对淀粉样蛋白-β42纤维形成动力学及其被Hsp104抑制的建模进行了描述。 • 简要讨论了使用核磁共振波谱法追踪蛋白质聚集的局限性和优势。

期刊

Journal of Molecular Biology

IF:

4.5

论文数:

619

被引数:

5.4W

机构

暂无机构信息

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